A neurological sign characterized by brief, irregular lapses in muscle tone causing a flapping tremor, most commonly seen when the hands are extended. It indicates metabolic encephalopathy, particularly liver failure.
From Greek 'a-' (not) + 'sterixis' (fixed position), literally meaning 'inability to maintain position.' The term was coined by neurologists in the mid-20th century to describe this specific type of movement disorder.
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