D-dimer

/di ˈdaɪmər/ noun

A protein fragment produced when fibrin clots are broken down by the body's natural clot-dissolving system. Elevated levels suggest recent clot formation and breakdown, useful for ruling out pulmonary embolism.

Named for its structure as a dimer (two units) of D-domains from fibrin degradation, identified in the 1970s. The 'D' refers to the specific molecular fragment created when plasmin cuts cross-linked fibrin.

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