As an adverb, it means toward or in the main business area of a city. As an adjective or noun, it refers to that central urban area itself, often filled with offices, shops, and tall buildings.
Formed in American English from 'down' + 'town' in the early 19th century, originally in New York City. It contrasted 'downtown' (closer to the harbor and business) with 'uptown' (more residential and elevated). The pattern then spread to other cities.
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