To put a muzzle on an animal; to silence or restrain someone from speaking (archaic usage).
From a- (prefix meaning 'to' or 'cause to be') plus muzzle (to cover the mouth), creating a verb meaning 'to put a muzzle on' or figuratively 'to silence.'
Amuzzle is a wonderfully direct word—it literally means preventing something from using its mouth, which is why it became a metaphor for silencing people's speech!
Complete word intelligence in one call. Free tier — 50 lookups/day.