Softening or degeneration of blood vessel walls, which can lead to weakness and potential rupture of the vessel.
From Greek 'angeion' (vessel) + 'malakia' (softness). This pathological term describes degenerative changes in vascular tissue, documented in 19th-century pathology.
Angiomalacia is essentially when blood vessel walls start to fall apart at a cellular level—this is different from hardening of arteries; instead, the vessel gets weak and mushy, which can lead to dangerous aneurysms.
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