An early Christian theological doctrine asserting that God the Father and God the Son have fundamentally dissimilar natures or essences.
From 'anomoeean' (Greek 'anomios' meaning dissimilar) plus the suffix '-ism.' A major position in Arian disputes of the 4th century CE.
This heresy almost won during a brief period in the 300s—if it had, Christianity would have a completely different understanding of the Trinity. One emperor supported them, making them nearly mainstream, but then the political winds shifted.
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