Opposed to or acting against corn, the grain crop or the condition affecting feet.
From anti- (against) + corn (Old French corne, from Latin cornu meaning horn, because corns on feet resemble small horns). The prefix anti- creates opposition to either the crop or the foot condition.
The term 'corn' comes from hard, horn-like growths on feet, and anticorn remedies have been used for centuries—medieval people would use pumice stones to fight these painful bumps.
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