An old name for acetanilide, an early fever-reducing medicine that was used before aspirin became widely available.
From anti- (against) + febrin (relating to fever). This pharmaceutical term emerged in the late 1800s when acetanilide was marketed as a modern fever treatment.
Antifebrin was one of the first synthetic drugs ever created—chemists didn't discover it by extracting it from plants, but actually synthesized it in a laboratory in 1886, marking a turning point where humans could invent medicine rather than just finding it in nature, though it turned out to have dangerous side effects.
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