Opposed to or preventing orgasmic response; relating to substances or conditions that inhibit sexual pleasure or climax.
From anti- + orgastic (relating to orgasm, from Greek orgasmos). This medical/pharmacological term emerged in the 20th century with discussion of drug side effects and sexual dysfunction.
Some antidepressants famously have 'antiorgastic' side effects—helping people's mood while paradoxically making sexual pleasure harder—which is why finding the right medication involves complicated conversations doctors sometimes still feel awkward having.
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