To cause blisters or sores on; to blister completely or thoroughly.
From 'be-' plus 'blain' (an archaic word for blister or sore, from Old English 'blægene'). Suggests complete coverage with painful blisters.
Medieval manuscripts used 'beblained' to describe plague victims or severe skin conditions—it's viscerally unpleasant, evoking diseased skin erupting all over the body.
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