To drive someone insane or to turn something into a state of chaos and confusion (British spelling).
From Bedlam + the suffix -ise (British spelling convention). The verb form emerged in the 18th-19th centuries to describe the process of becoming or making something bedlam-like.
This verb captures something uniquely British—the habit of turning proper nouns (especially famous places) into verbs to describe what they represent, like 'to bedlamise' means to create utter chaos.
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