The American spelling of cinchonisation; the process of treating with cinchona bark or quinine.
From cinchona + -ization (American suffix for making or becoming). The American -ization derives from the same Greek -izein root as British -isation.
American doctors used 'cinchonization' as a standard treatment in Southern states where malaria was endemic, and the practice saved countless lives before modern antimalarial drugs were developed.
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