To administer an enema to someone; to subject to treatment with a clyster.
From clyster + -ize (a verb-forming suffix meaning 'to subject to' or 'to treat with'). This follows standard English word formation patterns for medical procedures.
The verb 'clysterize' sounds absurd to modern ears, but it's a perfectly logical word-formation—doctors still 'catheterize' patients today using the exact same grammatical pattern that created 'clysterize' centuries ago.
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