The complex process by which liquid blood transforms into a solid clot to stop bleeding. This involves platelets and a cascade of clotting factors working together to form fibrin strands.
From Latin 'coagulare' meaning 'to curdle,' from 'cogere' (to drive together). The term originally described milk curdling but was applied to blood clotting in the 17th century, reflecting the similar transformation from liquid to solid.
Blood coagulation is like a molecular domino effect - each clotting factor activates the next in a precise sequence, amplifying the signal until you get a massive clot response! This cascade can go from zero to full clot in under 5 minutes.
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