A synthetic opioid antagonist drug that blocks the effects of opioids in the body, once studied as a potential pain reliever and addiction treatment.
Blend of 'cycl-' (relating to cycles/rings) + '-azocine' (a class of opioid-related compounds). Developed in the 1960s as researchers systematically modified opioid structures to find new therapeutic agents.
Cyclazocine was exciting to scientists because it seemed to do something almost contradictory—it blocked opium's addictive effects while still relieving pain. Unfortunately, patients reported strange hallucinations and dysphoria, so it never became widely used, but it paved the way for better opioid antagonists like naloxone.
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