To remove doggedly persistent or stubborn qualities from something; to make less determined or relentless.
From de- (removal) + doggedly (from 'dog,' suggesting animal-like persistence) + -ize (to make or become). An extremely rare word, likely a 19th-century coinage that never gained wide acceptance.
This is a wonderfully obscure word that probably sounds made-up but isn't—it captures the idea of taking away that dog-like stubbornness. You can almost hear someone saying 'we need to dedoggerelize our approach' instead of 'be less stubborn!'
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