The act or process of removing fatigue or tiredness from someone or something.
From de- + Latin fatigatio (weariness), with the suffix -tion indicating a noun of action. This scholarly term emerged in Middle English to describe the relief of exhaustion.
Medieval scholars and physicians actually studied 'defatigation' as a medical concept—they believed the body needed specific treatments to remove accumulated fatigue rather than just sleep. This shows how people in the past had completely different frameworks for understanding how bodies recover.
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