Changed so that a substance loses its natural properties or becomes unfit for its original purpose, often by adding chemicals.
From de- (removal) + nature + -ize (to make or become), with -ed suffix. The term emerged in the late 1800s to describe the process of chemically altering natural substances.
Denatured alcohol is deliberately made toxic so people won't drink it—it's a clever way governments use chemistry to prevent alcohol abuse while still allowing industrial use.
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