A substance or stimulus that produces or causes sensation in the body.
From Greek 'aisthesis' (sensation) + 'gen' (producer or origin). First used in medical and physiological literature in the late 1800s to describe sensation-triggering agents.
Pain, heat, cold, and pressure are all esthiogens in action—basically anything that wakes up your nervous system and makes you feel something is technically an esthesiogen!
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