To drain blood from a body or organism; to remove or lose blood to the point of severe weakness or death.
From Latin exsanguinatus, past participle of exsanguinare (ex- 'thoroughly' + sanguinis 'blood'). Medical term that entered English in the 17th century for bloodletting procedures.
Exsanguinate sounds like a horror movie term, but it's actually standard medical vocabulary used in surgery—surgeons exsanguinate a limb before operating to keep the surgical field blood-free and visible.
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