Built in or connected in a permanent way that can't be easily changed; inherent or deeply ingrained in someone's nature.
From 'hard' (not flexible) and 'wired' (connected by wires). Originally a literal computing/electronics term for permanent physical connections, now used metaphorically for anything inflexible.
When we say someone is 'hardwired' to do something, we're comparing their brain to a computer circuit that can't be reprogrammed—it's a pretty modern metaphor that started in tech but now describes human nature!
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