The passage of fluid, especially blood, through the circulatory system or lymphatic system to an organ or tissue. It represents the delivery of nutrients and oxygen to cells and the removal of waste products.
From Latin 'perfundere' meaning 'to pour through' (per- 'through' + fundere 'to pour'). The medical term emerged in the 17th century to describe the flow of blood through tissues, becoming central to understanding circulation and organ function.
Your brain uses 20% of your body's blood perfusion despite being only 2% of your body weight! This massive blood flow requirement means that even a brief interruption in cerebral perfusion can cause irreversible brain damage within minutes.
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