Weird, strange, or not working correctly; things that seem twisted or off.
From 'screw' (from Old French 'escroue'), with the informal '-y' suffix added. Metaphorically, if something is 'screwed up,' it's twisted wrong like a screw.
This is slang that works because screws are literally twisted—so if your day is 'screwy,' it's been 'twisted' in weird ways. Slang often borrows from physical objects to describe abstract problems.
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