The hardening and thickening of the aorta due to accumulation of plaque, calcium, or other deposits in its walls, a form of arteriosclerosis affecting the main artery.
From Greek 'aorta' (the main artery) plus 'sclerosis' (hardening). This term emerged in medical literature as physicians recognized and studied age-related and disease-related hardening of the aorta specifically.
Aortosclerosis is what happens when the aorta loses its flexibility—instead of stretching and bouncing back with each heartbeat, it becomes stiff and brittle, making your heart work harder and raising blood pressure throughout your body.
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