Exhausted, tired out, or worn down; tuckered out or extremely fatigued (dialectal or informal).
Combining 'be-' with 'tuckered,' which itself derives from 'tuck' meaning to weary or exhaust. The adjective intensifies the sense of fatigue through the 'be-' prefix.
'Betuckered' is American dialectal gold—it shows the 'be-' prefix still lives in regional English, creating words like 'all betuckered out' that nobody writes down but everyone understands in the right region.
Complete word intelligence in one call. Free tier — 50 lookups/day.