Cholinesterase

/ˌkoʊlɪnˈɛstəreɪs/ noun

Definition

An enzyme that breaks down acetylcholine, a neurotransmitter that carries signals between nerve cells and muscles, helping signals stop after they're delivered.

Etymology

From 'choline' (a B vitamin) + 'ester' (chemical compound) + '-ase' (enzyme suffix). Named for the molecule it breaks down.

Kelly Says

Nerve gas and pesticides work by poisoning cholinesterase—they paralyze it so acetylcholine builds up and muscles contract uncontrollably. Understanding this enzyme was crucial for both developing chemical weapons and creating antidotes.

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