The condition or state of being poisoned or intoxicated by datura; datura poisoning or datura intoxication.
From 'datura' plus the suffix '-ism' (meaning 'condition of' or 'practice of'). This medical term appears in 19th and 20th-century toxicology literature.
Early medical reports on 'daturism' described patients so violently hallucinating that they had to be physically restrained, which is why modern poison control centers warn so seriously about even small accidental exposures.
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