To dispose of; to arrange, settle, or put in order; an archaic or dialectal form.
From Old French 'desposer', combining 'des-' (apart) and 'poser' (to place). The meaning shifted over time from arranging/disposing to eventually being replaced by simpler words like 'dispose'.
Despose is so archaic that even scholars of Middle English have to look it up—it's one of those words that got abandoned because 'dispose' did the job better, showing how languages naturally prune their own redundancy.
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