Describing a person whose gender identity differs from the sex they were assigned at birth.
From 'trans-' (across, beyond, through) combined with 'gender.' The prefix 'trans-' comes from Latin meaning to cross over. The modern usage emerged in medical and psychological contexts in the late 20th century.
Medical science now shows that gender identity forms in the brain during prenatal development—it's not a choice but rather a fundamental aspect of neurology, which is why understanding transgender people requires understanding brain biology, not just social ideas about gender.
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