An atypical antipsychotic medication that blocks dopamine and serotonin receptors, used to treat schizophrenia, bipolar disorder, and sometimes major depression as an adjunct therapy. Known for its sedating properties.
A synthetic compound name developed by AstraZeneca, with the '-ine' suffix common in pharmaceutical nomenclature. First approved by the FDA in 1997 as part of the second generation of antipsychotics.
Quetiapine is nicknamed 'Quell' on the street because of its powerful sedating effects - it's sometimes misused as a sleep aid. Interestingly, at low doses it primarily blocks histamine receptors (causing drowsiness), while its antipsychotic effects only kick in at higher doses when it blocks dopamine receptors.
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